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Long-acting parenteral nanoformulated antiretroviral therapy: interest and attitudes of HIV-infected patients.


ABSTRACT: To gauge patient interest in receiving long-acting injectable nanoformulated antiretroviral therapy.Four hundred adult HIV-infected patients currently prescribed antiretroviral therapy were surveyed. ?(2) tests were used for comparisons of interest across groups.Respondents were 68% male and 53% African-American, with a mean age of 47 years. Overall, 73% of patients indicated that they would definitely or probably try injectable nanoformulated antiretroviral therapy; 61% with weekly dosing; 72% every 2 weekly; and 84% monthly. In total, 48% indicated that they were very concerned about the possible side effects and 35% were very concerned about needle use.The majority of respondents indicated that they definitely or probably would try parenteral nanoformulated antiretroviral therapy.

SUBMITTER: Williams J 

PROVIDER: S-EPMC3987826 | biostudies-other | 2013 Nov

REPOSITORIES: biostudies-other

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Long-acting parenteral nanoformulated antiretroviral therapy: interest and attitudes of HIV-infected patients.

Williams Jennifer J   Sayles Harlan R HR   Meza Jane L JL   Sayre Patrick P   Sandkovsky Uriel U   Gendelman Howard E HE   Flexner Charles C   Swindells Susan S  

Nanomedicine (London, England) 20130423 11


<h4>Aim</h4>To gauge patient interest in receiving long-acting injectable nanoformulated antiretroviral therapy.<h4>Methods</h4>Four hundred adult HIV-infected patients currently prescribed antiretroviral therapy were surveyed. χ(2) tests were used for comparisons of interest across groups.<h4>Results</h4>Respondents were 68% male and 53% African-American, with a mean age of 47 years. Overall, 73% of patients indicated that they would definitely or probably try injectable nanoformulated antiretr  ...[more]

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