Ontology highlight
ABSTRACT:
SUBMITTER: Rinehart M
PROVIDER: S-EPMC3988224 | biostudies-other | 2014
REPOSITORIES: biostudies-other
PloS one 20140415 4
We have developed a quantitative imaging refractometry technique, based on holographic phase microscopy, as a tool for investigating microscopic structural changes in water-soluble polymeric materials. Here we apply the approach to analyze the structural degradation of vaginal topical microbicide films due to water uptake. We implemented transmission imaging of 1-mm diameter film samples loaded into a flow chamber with a 1.5×2 mm field of view. After water was flooded into the chamber, interfere ...[more]