Ontology highlight
ABSTRACT:
SUBMITTER: Yoshioka Y
PROVIDER: S-EPMC3988821 | biostudies-other | 2014
REPOSITORIES: biostudies-other
Yoshioka Yusuke Y Kosaka Nobuyoshi N Konishi Yuki Y Ohta Hideki H Okamoto Hiroyuki H Sonoda Hikaru H Nonaka Ryoji R Yamamoto Hirofumi H Ishii Hideshi H Mori Masaki M Furuta Koh K Nakajima Takeshi T Hayashi Hiroshi H Sugisaki Hajime H Higashimoto Hiroko H Kato Takashi T Takeshita Fumitaka F Ochiya Takahiro T
Nature communications 20140407
Cancer cells secrete small membranous extracellular vesicles (EVs) into their microenvironment and circulation. Although their potential as cancer biomarkers has been promising, the identification and quantification of EVs in clinical samples remains challenging. Here we describe a sensitive and rapid analytical technique for profiling circulating EVs directly from blood samples of patients with colorectal cancer. EVs are captured by two types of antibodies and are detected by photosensitizer-be ...[more]