Ontology highlight
ABSTRACT:
SUBMITTER: Vekariya RH
PROVIDER: S-EPMC3993870 | biostudies-other | 2014 Apr
REPOSITORIES: biostudies-other
Organic letters 20140317 7
An intramolecular Huisgen cycloaddition of an interconverting set of isomeric allylic azides with alkynes affords substituted triazoles in high yield. The stereoisomeric vinyl-substituted triazoloxazines formed depend on the rate of cycloaddition of the different allylic azide precursors when the reaction is carried out under thermal conditions. In contrast, dimerized macrocyclic products were obtained when the reaction was done using copper(I)-catalyzed conditions, demonstrating the ability to ...[more]