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Integrated IVUS-OCT Imaging for Atherosclerotic Plaque Characterization.


ABSTRACT: For the diagnosis of atherosclerosis, biomedical imaging techniques such as intravascular ultrasound (IVUS) and optical coherence tomography (OCT) have been developed. The combined use of IVUS and OCT is hypothesized to remarkably increase diagnostic accuracy of vulnerable plaques. We have developed an integrated IVUS-OCT imaging apparatus, which includes the integrated catheter, motor drive unit, and imaging system. The dual-function imaging catheter has the same diameter of current clinical standard. The imaging system is capable for simultaneous IVUS and OCT imaging in real time. Ex vivo and in vivo experiments on rabbits with atherosclerosis were conducted to demonstrate the feasibility and superiority of the integrated intravascular imaging modality.

SUBMITTER: Li X 

PROVIDER: S-EPMC3996710 | biostudies-other | 2014 Mar

REPOSITORIES: biostudies-other

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Integrated IVUS-OCT Imaging for Atherosclerotic Plaque Characterization.

Li Xiang X   Li Jiawen J   Jing Joe J   Ma Teng T   Liang Shanshan S   Zhang Jun J   Mohar Dilbahar D   Raney Aidan A   Mahon Sari S   Brenner Matthew M   Patel Pranav P   Shung K Kirk KK   Zhou Qifa Q   Chen Zhongping Z  

IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society 20140301 2


For the diagnosis of atherosclerosis, biomedical imaging techniques such as intravascular ultrasound (IVUS) and optical coherence tomography (OCT) have been developed. The combined use of IVUS and OCT is hypothesized to remarkably increase diagnostic accuracy of vulnerable plaques. We have developed an integrated IVUS-OCT imaging apparatus, which includes the integrated catheter, motor drive unit, and imaging system. The dual-function imaging catheter has the same diameter of current clinical st  ...[more]

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