Unknown

Dataset Information

0

Allostatic load model associated with indoor environmental quality and sick building syndrome among office workers.


ABSTRACT: This study investigates whether indoor environmental quality (IEQ) influences allostatic load (AL) and whether AL can be a predictor for sick building syndrome (SBS). We also assessed and compared the associations between AL and SBS versus 8-hydroxydeoxyguanosine (8-OHdG) and SBS. A total of 115 office workers from 21 offices completed self-reported SBS questionnaires, and provided 11 biomarkers for their AL. Multiple linear regressions and logistic regression analysis were applied to examine the correlations between IEQ and AL or 8-OHdG and between AL or 8-OHdG and SBS, respectively. Our data revealed that the neuroendocrine system was correlated with CO2, the difference between indoor and outdoor CO2 levels (dCO2), and the indoor-outdoor ratio of CO2 (CO2 I/O). Metabolic system effects were associated with illumination. The relationships between illumination, CO2, dCO2, CO2 I/O and 8-OHdG were consistent with those and AL in specific systems. Furthermore, we found that risks for SBS syndromes were related with neuroendocrine and metabolic system of the AL. 8-OHdG was associated with eye dryness or irritation, eye tiredness and vomiting. We conclude that IEQ significantly influences AL and that AL can be a predictor for reporting SBS with information on system-specific effects.

SUBMITTER: Jung CC 

PROVIDER: S-EPMC3997416 | biostudies-other | 2014

REPOSITORIES: biostudies-other

Similar Datasets

| S-EPMC9518424 | biostudies-literature
| S-EPMC2092526 | biostudies-literature
| S-EPMC6533716 | biostudies-literature
| S-EPMC7143121 | biostudies-literature
| S-EPMC7437141 | biostudies-literature
| S-EPMC6086207 | biostudies-literature
| S-EPMC3874261 | biostudies-literature
| S-EPMC6360122 | biostudies-literature
| S-EPMC10375552 | biostudies-literature
| S-EPMC7705943 | biostudies-literature