Ontology highlight
ABSTRACT:
SUBMITTER: Zhang X
PROVIDER: S-EPMC4004327 | biostudies-other | 2014 Apr
REPOSITORIES: biostudies-other
Zhang Xinyue X Wang Yong Y Fricke Brandon L BL Gu Li-Qun LQ
ACS nano 20140326 4
Many efforts are being made in translating the nanopore into an ultrasensitive single-molecule platform for various genetic and epigenetic detections. However, compared with current approaches including PCR, the low throughput limits the nanopore applications in biological research and clinical settings, which usually requires simultaneous detection of multiple biomarkers for accurate disease diagnostics. Herein we report a barcode probe approach for multiple nucleic acid detection in one nanopo ...[more]