Cholesterol's aliphatic side chain modulates membrane properties.
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ABSTRACT:
SUBMITTER: Scheidt HA
PROVIDER: S-EPMC4011182 | biostudies-other | 2013 Dec
REPOSITORIES: biostudies-other
Publications
Cholesterol's aliphatic side chain modulates membrane properties.
Scheidt Holger A HA Meyer Thomas T Nikolaus Jörg J Baek Dong Jae DJ Haralampiev Ivan I Thomas Lars L Bittman Robert R Müller Peter P Herrmann Andreas A Huster Daniel D
Angewandte Chemie (International ed. in English) 20131125 49
The influence of cholesterol's alkyl side chain on membrane properties was studied using a series of synthetic cholesterol derivatives without a side chain or with a branched side chain consisting of 5 to 14 carbon atoms. Cholesterol's side chain is crucial for all membrane properties investigated and therefore essential for the membrane properties of eukaryotic cells. ...[more]
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