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Methyl ({[(4E)-1,3-dimethyl-2,6-di-phenyl-piperidin-4-yl-idene]amino}-oxy)acetate.

ABSTRACT: In the title compound, C22H26N2O3, the piperidine ring exhibits a chair conformation. The phenyl rings attached to the piperidine at the 2- and 6-positions have axial orientations. These rings make a dihedral angle of 49.75?(11)°. The amino-oxy acetate group attached at the 4-position has an equatorial orientation. In the crystal, inversion dimers linked by pairs of C-H?? inter-actions occur.

SUBMITTER: Mohandas T

PROVIDER: S-EPMC4011218 | biostudies-other | 2014 May

REPOSITORIES: biostudies-other

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Methyl ({[(4E)-1,3-dimethyl-2,6-di-phenyl-piperidin-4-yl-idene]amino}-oxy)acetate.

Mohandas T T Pillai M Velayutham MV Vidhyasagar T T Pasupathy A A Sakthivel P P

Acta crystallographica. Section E, Structure reports online 20140402 Pt 5

In the title compound, C22H26N2O3, the piperidine ring exhibits a chair conformation. The phenyl rings attached to the piperidine at the 2- and 6-positions have axial orientations. These rings make a dihedral angle of 49.75 (11)°. The amino-oxy acetate group attached at the 4-position has an equatorial orientation. In the crystal, inversion dimers linked by pairs of C-H⋯π inter-actions occur. ...[more]

PMID: 24860328

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(E)-1,3-Dimethyl-2,6-di-phenyl-piperidin-4-one O-(phen-oxy-carbon-yl)oxime.

Project description:The title piperidine derivative, C26H26N2O3, has an E conformation about the N=C bond. The piperidine ring has a chair conformation and its mean plane is almost perpendicular to the attached phenyl rings, making dihedral angles of 87.47?(9) and 87.34?(8)°. The planes of these two phenyl rings are inclined to one another by 60.38?(9)°. The plane of the terminal phenyl ring is tilted at an angle of 32.79?(9)° to the mean plane of the piperidine ring. The mol-ecular conformation is stabilized by two intra-molecular C-H?O contacts. There are no significant inter-molecular inter-actions in the crystal.

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Project description:In the title compound, C(26)H(27)BrN(2)O, the piperidine ring has a chair conformation and all ring substituents occupy equatorial positions, apart from the double-bonded N atom, which occupies a bis-ectional position. The dihedral angle formed between the phenyl rings is 61.18?(19)°, and the phenyl rings form dihedral angles of 49.78?(19) and 69.2?(18)° with the bromo-benzene ring. The latter is coplanar with the meth-oxy(methyl-idene)amine fragment [N-O-C-C torsion angle = -171.7?(2)°]. Linear supra-molecular chains, approximately along [112], sustained by C-H?? inter-actions, feature in the crystal packing.

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Project description:In the title compound, C(26)H(27)ClN(2)O, the piperidine ring has a chair conformation and all of the ring substituents at Csp(3) atoms occupy equatorial positions. The dihedral angle formed between the phenyl rings is 48.11?(9)°. The chloro-benzene ring occupies a position orthogonal to the meth-oxy(methyl-idene)amine residue [N-O-C-C torsion angle = -87.90?(15)°]. The conformation about the imine C=N bond [1.278?(2)?Å] is E, and the chloro substituent is anti to the piperidine N atom. Helical supra-molecular chains along [010] are sustained by C-H?? inter-actions in the crystal packing.

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Crystal structures of (E)-(3-ethyl-1-methyl-2,6-di-phenyl-piperidin-4-yl-idene)amino phenyl carbonate and (E)-(3-isopropyl-1-methyl-2,6-di-phenyl-piperidin-4-yl-idene)amino phenyl carbonate.

Project description:In the title compounds, C27H28N2O3, (I), and C28H30N2O3, (II), the conformation about the C=N bond is E. The piperidine rings adopt chair conformations with the attached phenyl rings almost normal to their mean planes, the dihedral angles being 85.82?(8) and 85.84?(7)° in (I), and 87.98?(12) and 86.42?(13)° in (II). The phenyl rings are inclined to one another by 52.87?(8)° in (I) and by 60.51?(14)° in (II). The main difference in the conformation of the two compounds is the angle of inclination of the phen-oxy-carbonyl ring to the piperidine ring mean plane. In (I), these two planes are almost coplanar, with a dihedral angle of 2.05?(8)°, while in (II), this angle is 45.24?(13)°. In the crystal of (I), mol-ecules are linked by C-H?O hydrogen bonds, forming inversion dimers with R 2 (2)(14) loops. The dimers are linked via C-H?? inter-actions forming a three-dimensional network. In the crystal of (II), there are no significant inter-molecular inter-actions present.

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Project description:In the title compound, C19H23N, the piperidine ring has a chair conformation. The phenyl rings are inclined to one another by 52.76 (16)°. One of the methyl substituents on the piperidine ring is axial while the other is equatorial, like the phenyl rings. In the crystal, mol-ecules are linked via C-H⋯π inter-actions, forming zigzag chains along [001].

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Project description:In the title mol-ecule, C(21)H(25)NO, the piperidine ring adopts a chair conformation. The benzene rings and one of the methyl groups attached to the piperidine ring have equatorial orientations. The dihedral angle between the two benzene rings is 72.53?(9)°. In the crystal, mol-ecules are linked by N-H?O hydrogen bonds. Weak C-H?? inter-actions involving the benzene rings are also present in the crystal structure.

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