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Maleimide-functionalised platinum(IV) complexes as a synthetic platform for targeted drug delivery.

ABSTRACT: Maleimide-functionalised Pt(IV) complexes with highly selective binding properties to thiol groups were synthesised as precursors for binding of thiol-containing tumour-targeting molecules like human serum albumin.

SUBMITTER: Pichler V 

PROVIDER: S-EPMC4021452 | biostudies-other | 2013 Mar

REPOSITORIES: biostudies-other

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Maleimide-functionalised platinum(IV) complexes as a synthetic platform for targeted drug delivery.

Pichler Verena V   Mayr Josef J   Heffeter Petra P   Dömötör Orsolya O   Enyedy Éva A ÉA   Hermann Gerrit G   Groza Diana D   Köllensperger Gunda G   Galanksi Markus M   Berger Walter W   Keppler Bernhard K BK   Kowol Christian R CR  

Chemical communications (Cambridge, England) 20130301 22

Maleimide-functionalised Pt(IV) complexes with highly selective binding properties to thiol groups were synthesised as precursors for binding of thiol-containing tumour-targeting molecules like human serum albumin. ...[more]

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