Ontology highlight
ABSTRACT:
SUBMITTER: Vaccaro V
PROVIDER: S-EPMC4024398 | biostudies-other | 2014
REPOSITORIES: biostudies-other
Vaccaro V V Fabi A A Vidiri A A Giannarelli D D Metro G G Telera S S Vari S S Piludu F F Carosi M A MA Villani V V Cognetti F F Pompili A A Marucci L L Carapella C M CM Pace A A
BioMed research international 20140504
<h4>Background</h4>No established chemotherapeutic regimen exists for the treatment of recurrent malignant gliomas (rMGs). Herein, we report the activity and safety results of the bevacizumab (B) plus fotemustine (FTM) combination for the treatment of rMGs.<h4>Patients and methods</h4>An induction phase consisted of B 10 mg/kg days 1, 15 plus FTM 65 mg/m(2) days 1, 8, and 15. Nonprogressive patients entered the maintenance phase with B 10 mg/kg plus FTM 75 mg/m(2) every 3 weeks. The primary endp ...[more]