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Using medicinal chemistry to solve an old medical mystery.


ABSTRACT: The logic behind the traditional medicinal chemistry technique of designing a synthetic enzyme substrate to mimic a natural one is used to uncover the identity of the unknown cause of two legacy industrial diseases by comparing the reported symptoms to two side effects of a modern synthetic.

SUBMITTER: Hinshaw WB 

PROVIDER: S-EPMC4027553 | biostudies-other | 2013 Jan

REPOSITORIES: biostudies-other

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