Improving the plausibility of success with inefficient metrics.
Ontology highlight
ABSTRACT: To increase the probability of success in drug discovery, the concept of drug-like properties was introduced. Efficiency metrics that normalize potency against these properties could help reach drug-like space more efficiently. Potential reasons for the inefficient use of metrics and suboptimal decision making are discussed.
SUBMITTER: Shultz MD
PROVIDER: S-EPMC4027587 | biostudies-other | 2014 Jan
REPOSITORIES: biostudies-other
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