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Tunable visible and near-IR photoactivation of light-responsive compounds by using fluorophores as light-capturing antennas.

ABSTRACT: Although the corrin ring of vitamin B12 is unable to efficiently absorb light beyond 550 nm, it is shown that commercially available fluorophores can be used as antennas to capture long-wavelength light to promote scission of the Co-C bond at wavelengths up to 800 nm. The ability to control the molecular properties of bioactive species with long visible and near-IR light has implications for drug delivery, nanotechnology, and the spatiotemporal control of cellular behavior.

SUBMITTER: Shell TA

PROVIDER: S-EPMC4036634 | biostudies-other | 2014 Jan

REPOSITORIES: biostudies-other

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Tunable visible and near-IR photoactivation of light-responsive compounds by using fluorophores as light-capturing antennas.

Shell Thomas A TA Shell Jennifer R JR Rodgers Zachary L ZL Lawrence David S DS

Angewandte Chemie (International ed. in English) 20131127 3

Although the corrin ring of vitamin B12 is unable to efficiently absorb light beyond 550 nm, it is shown that commercially available fluorophores can be used as antennas to capture long-wavelength light to promote scission of the Co-C bond at wavelengths up to 800 nm. The ability to control the molecular properties of bioactive species with long visible and near-IR light has implications for drug delivery, nanotechnology, and the spatiotemporal control of cellular behavior. ...[more]

PMID: 24285381

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