Ontology highlight
ABSTRACT:
SUBMITTER: Cheung CW
PROVIDER: S-EPMC4049244 | biostudies-other | 2014 Jun
REPOSITORIES: biostudies-other
The Journal of organic chemistry 20140506 11
A method for the hydroxylation of aryl and heteroaryl halides, promoted by a catalyst based on a biarylphosphine ligand tBuBrettPhos (L5) and its corresponding palladium precatalyst (1), is described. The reactions allow the cross-coupling of both potassium and cesium hydroxides with (hetero)aryl halides to afford a variety of phenols and hydroxylated heteroarenes in high to excellent yield. ...[more]