Ontology highlight
ABSTRACT:
SUBMITTER: Megraw M
PROVIDER: S-EPMC4054853 | biostudies-other | 2013 Aug
REPOSITORIES: biostudies-other
Genome biology 20130823 8
WaRSwap is a randomization algorithm that for the first time provides a practical network motif discovery method for large multi-layer networks, for example those that include transcription factors, microRNAs, and non-regulatory protein coding genes. The algorithm is applicable to systems with tens of thousands of genes, while accounting for critical aspects of biological networks, including self-loops, large hubs, and target rearrangements. We validate WaRSwap on a newly inferred regulatory net ...[more]