New insights into the role of histamine in subventricular zone-olfactory bulb neurogenesis.
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ABSTRACT:
SUBMITTER: Eiriz MF
PROVIDER: S-EPMC4058902 | biostudies-other | 2014
REPOSITORIES: biostudies-other
Publications
New insights into the role of histamine in subventricular zone-olfactory bulb neurogenesis.
Eiriz Maria F MF Valero Jorge J Malva João O JO Bernardino Liliana L
Frontiers in neuroscience 20140616
The subventricular zone (SVZ) contains neural stem cells (NSCs) that generate new neurons throughout life. Many brain diseases stimulate NSCs proliferation, neuronal differentiation and homing of these newborns cells into damaged regions. However, complete cell replacement has never been fully achieved. Hence, the identification of proneurogenic factors crucial for stem cell-based therapies will have an impact in brain repair. Histamine, a neurotransmitter and immune mediator, has been recently ...[more]
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