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The billion cell construct: will three-dimensional printing get us there?


ABSTRACT: How structure relates to function--across spatial scales, from the single molecule to the whole organism--is a central theme in biology. Bioengineers, however, wrestle with the converse question: will function follow form? That is, we struggle to approximate the architecture of living tissues experimentally, hoping that the structure we create will lead to the function we desire. A new means to explore the relationship between form and function in living tissue has arrived with three-dimensional printing, but the technology is not without limitations.

SUBMITTER: Miller JS 

PROVIDER: S-EPMC4061004 | biostudies-other | 2014 Jun

REPOSITORIES: biostudies-other

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The billion cell construct: will three-dimensional printing get us there?

Miller Jordan S JS  

PLoS biology 20140617 6


How structure relates to function--across spatial scales, from the single molecule to the whole organism--is a central theme in biology. Bioengineers, however, wrestle with the converse question: will function follow form? That is, we struggle to approximate the architecture of living tissues experimentally, hoping that the structure we create will lead to the function we desire. A new means to explore the relationship between form and function in living tissue has arrived with three-dimensional  ...[more]

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