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Phenylthiocarbamate or N-carbothiophenyl group chemistry in peptide synthesis and bioconjugation.


ABSTRACT: The design of novel chemoselective and site-specific ligation methods provides new tools for obtaining complex scaffolds, peptidomimetics, and peptide conjugates. The chemistry of the N-phenylthiocarbonyl group has led to several developments in peptide ligation chemistry and peptide bioconjugation during the last 10 years. The aim of this review is to provide an overview of this emerging field.

SUBMITTER: Melnyk O 

PROVIDER: S-EPMC4064696 | biostudies-other | 2014 Apr

REPOSITORIES: biostudies-other

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