Ontology highlight
ABSTRACT:
SUBMITTER: Xiao J
PROVIDER: S-EPMC4081006 | biostudies-other | 2013 Dec
REPOSITORIES: biostudies-other
Journal of neural transmission (Vienna, Austria : 1996) 20130703 12
Since Toxoplasma gondii can establish a persistent infection in the central nervous system in humans, we studied its effects on a host's neurotransmitter and neuropeptide systems (NNS). Using microarray technology, we have screened the expression of genes coding for NNS in human neuroepithelioma cells in response to representative strains of Toxoplasma to identify potential target genes. Transcripts that displayed expression levels distinct from uninfected controls were examined by RT-PCR and We ...[more]