Ontology highlight
ABSTRACT:
SUBMITTER: Regulski M
PROVIDER: S-EPMC40926 | biostudies-other | 1995 Sep
REPOSITORIES: biostudies-other
Proceedings of the National Academy of Sciences of the United States of America 19950901 20
Nitric oxide (NO) is an intercellular messenger involved with various aspects of mammalian physiology ranging from vasodilation and macrophage cytotoxicity to neuronal transmission. NO is synthesized from L-arginine by NO synthase (NOS). Here, we report the cloning of a Drosophila NOS gene, dNOS, located at cytological position 32B. The dNOS cDNA encodes a protein of 152 kDa, with 43% amino acid sequence identity to rat neuronal NOS. Like mammalian NOSs, DNOS protein contains putative binding si ...[more]