Ontology highlight
ABSTRACT:
SUBMITTER: Lam SM
PROVIDER: S-EPMC4099521 | biostudies-other | 2014 Oct
REPOSITORIES: biostudies-other
Lam Sin Man SM Wang Yuting Y Duan Xinrui X Wenk Markus R MR Kalaria Raj N RN Chen Christopher P CP Lai Mitchell K P MK Shui Guanghou G
Neurobiology of aging 20140301 10
Despite its importance as the leading cause of vascular dementia, the primary pathogenic mechanisms in subcortical ischemic vascular dementia (SIVD) have remained elusive. Because of the lack of approved therapeutic agents for SIVD, there is a pressing need to identify novel therapeutic targets. Comparative lipidomic analyses of SIVD and mixed dementia (i.e., SIVD and Alzheimer's disease, MixD) may also confer new insights pertaining to the possible interaction between neurodegenerative and vasc ...[more]