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The core Escherichia coli signal recognition particle receptor contains only the N and G domains of FtsY.


ABSTRACT: Previous studies have proposed that the N-terminal A domain (approximately 200 amino acid residues) of the Escherichia coli signal recognition particle (SRP) receptor, FtsY, is required for membrane targeting. In contrast to this suggestion, we show that A domain-truncated versions of FtsY, harboring only domains N and G, are functional. Therefore, we propose that N and G domains constitute the core SRP receptor.

SUBMITTER: Eitan A 

PROVIDER: S-EPMC412183 | biostudies-other | 2004 Apr

REPOSITORIES: biostudies-other

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