Ontology highlight
ABSTRACT:
SUBMITTER: Watanabe R
PROVIDER: S-EPMC4124872 | biostudies-other | 2014
REPOSITORIES: biostudies-other
Watanabe Rikiya R Soga Naoki N Fujita Daishi D Tabata Kazuhito V KV Yamauchi Lisa L Hyeon Kim Soo S Asanuma Daisuke D Kamiya Mako M Urano Yasuteru Y Suga Hiroaki H Noji Hiroyuki H
Nature communications 20140724
Nano- to micron-size reaction chamber arrays (femtolitre chamber arrays) have facilitated the development of sensitive and quantitative biological assays, such as single-molecule enzymatic assays, digital PCR and digital ELISA. However, the versatility of femtolitre chamber arrays is limited to reactions that occur in aqueous solutions. Here we report an arrayed lipid bilayer chamber system (ALBiC) that contains sub-million femtolitre chambers, each sealed with a stable 4-μm-diameter lipid bilay ...[more]