Disrupted posterior cingulate-amygdala connectivity in postpartum depressed women as measured with resting BOLD fMRI.
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ABSTRACT:
SUBMITTER: Chase HW
PROVIDER: S-EPMC4127008 | biostudies-other | 2014 Aug
REPOSITORIES: biostudies-other
Publications
Disrupted posterior cingulate-amygdala connectivity in postpartum depressed women as measured with resting BOLD fMRI.
Chase Henry W HW Moses-Kolko Eydie L EL Zevallos Carlos C Wisner Katherine L KL Phillips Mary L ML
Social cognitive and affective neuroscience 20130523 8
Disengagement of emotion regulation circuits was previously shown in depressed mothers and was hypothesized to underlie the impaired maternal-infant sensitivity described in postpartum depression (PPD). We hypothesized similarly reduced resting-state functional connectivity in default mode network (DMN) regions involved in social cognition in PPD. Resting-state functional MRI, clinical and mother-infant attachment data were obtained from 14 unmedicated postpartum women with major depression and ...[more]
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