Ontology highlight
ABSTRACT:
SUBMITTER: Zapol'skii VA
PROVIDER: S-EPMC4142838 | biostudies-other | 2014
REPOSITORIES: biostudies-other
Beilstein journal of organic chemistry 20140717
The reaction of mercaptoacetic acid esters with pentachloro-2-nitro-1,3-butadiene (1) provides an appropriate precursor for the synthesis of special thiazolidin-4-ones. Applying different anilines as the second constituent for the requisite cyclization step, a series of (Z)-2-allylidenethiazolidin-4-ones was obtained in yields up to 81%. Some subsequent reactions have been examined too, such as the formation of perfunctionalized 1H-pyrazoles upon treatment with hydrazine. Thiazolidinones are as ...[more]