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Prognostic biomarkers in ovarian cancer.


ABSTRACT: Epithelial ovarian cancer (EOC) remains the most lethal gynecological malignancy despite several decades of progress in diagnosis and treatment. Taking advantage of the robust development of discovery and utility of prognostic biomarkers, clinicians and researchers are developing personalized and targeted treatment strategies. This review encompasses recently discovered biomarkers of ovarian cancer, the utility of published prognostic biomarkers for EOC (especially biomarkers related to angiogenesis and key signaling pathways), and their integration into clinical practice.

SUBMITTER: Huang J 

PROVIDER: S-EPMC4143980 | biostudies-other | 2010-2011

REPOSITORIES: biostudies-other

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Prognostic biomarkers in ovarian cancer.

Huang Jie J   Hu Wei W   Sood Anil K AK  

Cancer biomarkers : section A of Disease markers 20100101 4-5


Epithelial ovarian cancer (EOC) remains the most lethal gynecological malignancy despite several decades of progress in diagnosis and treatment. Taking advantage of the robust development of discovery and utility of prognostic biomarkers, clinicians and researchers are developing personalized and targeted treatment strategies. This review encompasses recently discovered biomarkers of ovarian cancer, the utility of published prognostic biomarkers for EOC (especially biomarkers related to angiogen  ...[more]

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