Ontology highlight
ABSTRACT:
SUBMITTER: Hou JP
PROVIDER: S-EPMC4148527 | biostudies-other | 2014
REPOSITORIES: biostudies-other
Genome medicine 20140731 7
Large-scale cancer genomic studies have revealed that the genetic heterogeneity of the same type of cancer is greater than previously thought. A key question in cancer genomics is the identification of driver genes. Although existing methods have identified many common drivers, it remains challenging to predict personalized drivers to assess rare and even patient-specific mutations. We developed a new algorithm called DawnRank to directly prioritize altered genes on a single patient level. Appli ...[more]