RNA epigenetics.
Ontology highlight
ABSTRACT:
SUBMITTER: Liu N
PROVIDER: S-EPMC4190089 | biostudies-other | 2015 Jan
REPOSITORIES: biostudies-other
Publications
RNA epigenetics.
Translational research : the journal of laboratory and clinical medicine 20140408 1
Mammalian messenger RNA (mRNA) and long noncoding RNA (lncRNA) contain tens of thousands of posttranscriptional chemical modifications. Among these, the N(6)-methyl-adenosine (m(6)A) modification is the most abundant and can be removed by specific mammalian enzymes. m(6)A modification is recognized by families of RNA binding proteins that affect many aspects of mRNA function. mRNA/lncRNA modification represents another layer of epigenetic regulation of gene expression, analogous to DNA methylati ...[more]
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