Development of Streptococcus pneumoniae Vaccines Using Live Vectors.
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ABSTRACT:
SUBMITTER: Wang S
PROVIDER: S-EPMC4192125 | biostudies-other | 2014 Jan
REPOSITORIES: biostudies-other
Publications
Development of <i>Streptococcus pneumoniae</i> Vaccines Using Live Vectors.
Vaccines 20140101 1
<i>Streptococcus pneumoniae</i> still causes severe morbidity and mortality worldwide, especially in young children and the elderly. Much effort has been dedicated to developing protein-based universal vaccines to conquer the current shortcomings of capsular vaccines and capsular conjugate vaccines, such as serotype replacement, limited coverage and high costs. A recombinant live vector vaccine delivering protective antigens is a promising way to achieve this goal. In this review, we discuss the ...[more]
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