Ontology highlight
ABSTRACT:
SUBMITTER: Wenz LS
PROVIDER: S-EPMC4197878 | biostudies-other | 2014 Jun
REPOSITORIES: biostudies-other
EMBO reports 20140429 6
The mitochondrial outer membrane contains integral α-helical and β-barrel proteins that are imported from the cytosol. The machineries importing β-barrel proteins have been identified, however, different views exist on the import of α-helical proteins. It has been reported that the biogenesis of Om45, the most abundant signal-anchored protein, does not depend on proteinaceous components, but involves direct insertion into the outer membrane. We show that import of Om45 occurs via the translocase ...[more]