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The acidic nature of the CcmG redox-active center is important for cytochrome c maturation in Escherichia coli.


ABSTRACT: Cytochrome c biogenesis in Escherichia coli is a complex process requiring at least eight genes (ccmABCDEFGH). One of these genes, ccmG, encodes a thioredoxin-like protein with unusually specific redox activity. Here, we investigate the basis for CcmG function and demonstrate the importance of acidic residues surrounding the redox-active center.

SUBMITTER: Edeling MA 

PROVIDER: S-EPMC419958 | biostudies-other | 2004 Jun

REPOSITORIES: biostudies-other

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