The acidic nature of the CcmG redox-active center is important for cytochrome c maturation in Escherichia coli.
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ABSTRACT: Cytochrome c biogenesis in Escherichia coli is a complex process requiring at least eight genes (ccmABCDEFGH). One of these genes, ccmG, encodes a thioredoxin-like protein with unusually specific redox activity. Here, we investigate the basis for CcmG function and demonstrate the importance of acidic residues surrounding the redox-active center.
SUBMITTER: Edeling MA
PROVIDER: S-EPMC419958 | biostudies-other | 2004 Jun
REPOSITORIES: biostudies-other
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