Ontology highlight
ABSTRACT:
SUBMITTER: Iwashita M
PROVIDER: S-EPMC4206826 | biostudies-other | 2014 Sep
REPOSITORIES: biostudies-other
eLife 20140930
Dopamine is critical for higher neural processes and modifying the activity of the prefrontal cortex (PFC). However, the mechanism of dopamine contribution to the modification of neural representation is unclear. Using in vivo two-photon population Ca(2+) imaging in awake mice, this study investigated how neural representation of visual input to PFC neurons is regulated by dopamine. Phasic stimulation of dopaminergic neurons in the ventral tegmental area (VTA) evoked prolonged Ca(2+) transients, ...[more]