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Microbicides and their potential as a catalyst for multipurpose sexual and reproductive health technologies.


ABSTRACT: There is an urgent need for technologies to prevent sexual acquisition of HIV infection in young women in sub-Saharan Africa. After two decades of 11 pivotal trials of seven products, anti-retroviral-based topical microbicides are showing promise. Building on the CAPRISA 004 trial findings, several trials of new anti-viral agents, novel delivery mechanisms and combination/multipurpose products that address challenges of adherence and meet the sexual and reproductive health needs of men and women, including preventing HIV infection, are underway.

SUBMITTER: Karim QA 

PROVIDER: S-EPMC4206831 | biostudies-other | 2014 Oct

REPOSITORIES: biostudies-other

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Microbicides and their potential as a catalyst for multipurpose sexual and reproductive health technologies.

Karim Q Abdool QA   Baxter C C   Karim S Abdool SA  

BJOG : an international journal of obstetrics and gynaecology 20141001


There is an urgent need for technologies to prevent sexual acquisition of HIV infection in young women in sub-Saharan Africa. After two decades of 11 pivotal trials of seven products, anti-retroviral-based topical microbicides are showing promise. Building on the CAPRISA 004 trial findings, several trials of new anti-viral agents, novel delivery mechanisms and combination/multipurpose products that address challenges of adherence and meet the sexual and reproductive health needs of men and women  ...[more]

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