Detecting "different": Pyrin senses modified GTPases.
Ontology highlight
ABSTRACT: Pathogenic bacteria secrete effector proteins that target host cell Rho GTPases to manipulate the actin cytoskeleton. A recent study in Nature identifies the Pyrin inflammasome as a sensor of this pathogenic process.
SUBMITTER: de Zoete MR
PROVIDER: S-EPMC4220150 | biostudies-other | 2014 Nov
REPOSITORIES: biostudies-other
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