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Purpura fulminans and late onset group B streptococcal sepsis in a premature twin.


ABSTRACT: INTRODUCTION:  Purpura fulminans (PF) is a skin manifestation due to hemorrhagic infarction caused by intravascular thrombosis secondary to bacterial infections or deficiency of anticoagulants such as protein C and protein S. Neonatal PF is a rare but potentially disabling disorder associated with a high mortality and severe long term morbidity in those who survive. CASE DESCRIPTION:  We report a case of a premature infant who developed extensive PF due to late onset group B streptococcus sepsis. Despite early identification and initiation of antibiotic therapy in our patient, PF progressed rapidly, leading to autoamputation of fingers and toes and severe brain injury. CONCLUSION:  In conclusion, our case highlights the severe sequelae of PF due to late onset GBS sepsis in a premature infant.

SUBMITTER: Elayappen A 

PROVIDER: S-EPMC4239141 | biostudies-other | 2014 Nov

REPOSITORIES: biostudies-other

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