Anti-Inflammatory and Antihyperalgesic Activities of Ethanolic Extract and Fruticulin A from Salvia lachnostachys Leaves in Mice.
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ABSTRACT:
SUBMITTER: Piccinelli AC
PROVIDER: S-EPMC4241566 | biostudies-other | 2014
REPOSITORIES: biostudies-other
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Anti-Inflammatory and Antihyperalgesic Activities of Ethanolic Extract and Fruticulin A from Salvia lachnostachys Leaves in Mice.
Piccinelli Ana Claudia AC Figueiredo de Santana Aquino Diana D Morato Priscila Neder PN Kuraoka-Oliveira Angela Midori AM Strapasson Regiane Lauriano Batista RL Dos Santos Elide Pereira EP Stefanello Maria Élida Alves MÉ Oliveira Rodrigo Juliano RJ Oliveira Rodrigo Juliano RJ Kassuya Cândida Aparecida Leite CA
Evidence-based complementary and alternative medicine : eCAM 20141110
The anti-inflammatory and analgesic effects of the ethanolic extract (SLEE) and fruticulin A from the leaves of Salvia lachnostachys were evaluated in mice, using experimental models of inflammation (paw oedema and pleurisy induced by carrageenan injection) and hyperalgesia (electronic Von Frey). Oral administration of SLEE (30, 100, and 300 mg/kg) and fruticulin A (0.3 and 3.0 mg/kg) decreased the total leucocytes number in pleural lavage, protein extravasation, and paw oedema. SLEE (100 mg/kg) ...[more]
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