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Links between osteoarthritis and diabetes: implications for management from a physical activity perspective.


ABSTRACT: Osteoarthritis (OA) and type 2 diabetes mellitus (T2DM) often coexist in older adults. Those with T2DM are more susceptible to developing arthritis, which has been traditionally attributed to common risk factors, namely, age and obesity. Alterations in lipid metabolism and hyperglycemia might directly impact cartilage health and subchondral bone, contributing to the development/progression of OA. Adequate management of older persons with both conditions benefits from a comprehensive understanding of the associated risk factors. We discuss common risk factors and emerging links between OA and T2DM, emphasizing the importance of physical activity and the implications of safe and effective physical activity.

SUBMITTER: Piva SR 

PROVIDER: S-EPMC4254543 | biostudies-other | 2015 Feb

REPOSITORIES: biostudies-other

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Links between osteoarthritis and diabetes: implications for management from a physical activity perspective.

Piva Sara R SR   Susko Allyn M AM   Khoja Samannaaz S SS   Josbeno Deborah A DA   Fitzgerald G Kelley GK   Toledo Frederico G S FG  

Clinics in geriatric medicine 20141007 1


Osteoarthritis (OA) and type 2 diabetes mellitus (T2DM) often coexist in older adults. Those with T2DM are more susceptible to developing arthritis, which has been traditionally attributed to common risk factors, namely, age and obesity. Alterations in lipid metabolism and hyperglycemia might directly impact cartilage health and subchondral bone, contributing to the development/progression of OA. Adequate management of older persons with both conditions benefits from a comprehensive understandin  ...[more]

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