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Crystal structure of 2-[4-(methyl-sulfan-yl)quinazolin-2-yl]-1-phenyl-ethanol.

ABSTRACT: In the mol-ecule of the title compound, C17H16N2OS, the almost planar methyl-sulfanylquinazoline group [the methyl C atom deviates by 0.032?(2)?Å from the plane through the ring system] forms an inter-planar angle of 76.26?(4)° with the plane of the phenyl group. An intra-molecular O-H?N hydrogen bond is present between the quinazoline and hy-droxy groups. In the crystal, mol-ecules are stacked along the b-axis direction.

SUBMITTER: El-Hiti GA

PROVIDER: S-EPMC4257174 | biostudies-other | 2014 Oct

REPOSITORIES: biostudies-other

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Crystal structure of 2-[4-(methyl-sulfan-yl)quinazolin-2-yl]-1-phenyl-ethanol.

El-Hiti Gamal A GA Smith Keith K Hegazy Amany S AS Ajarim Mansour D MD Kariuki Benson M BM

Acta crystallographica. Section E, Structure reports online 20140910 Pt 10

In the mol-ecule of the title compound, C17H16N2OS, the almost planar methyl-sulfanylquinazoline group [the methyl C atom deviates by 0.032 (2) Å from the plane through the ring system] forms an inter-planar angle of 76.26 (4)° with the plane of the phenyl group. An intra-molecular O-H⋯N hydrogen bond is present between the quinazoline and hy-droxy groups. In the crystal, mol-ecules are stacked along the b-axis direction. ...[more]

PMID: 25484694

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