Ontology highlight
ABSTRACT:
SUBMITTER: Choi JS
PROVIDER: S-EPMC4259407 | biostudies-other | 2014 Oct
REPOSITORIES: biostudies-other
Oncotarget 20141001 20
HS-1-associated protein X-1 (HAX1) is a multi-functional protein which was first identified as a Hematopoietic cell specific Lyn Substrate 1 (HS1)-binding protein. Although the roles of HAX1 in apoptosis have been unraveled and HAX1 has been proposed to be involved in several diseases, additional roles of HAX1 are still being identified. Here, we demonstrated that HAX1 directly interacted with cellular Inhibitor of Apoptosis Proteins (cIAPs), ubiquitin E3 ligases which regulate the abundance of ...[more]