Ontology highlight
ABSTRACT:
SUBMITTER: Champagne DE
PROVIDER: S-EPMC42686 | biostudies-other | 1995 Jan
REPOSITORIES: biostudies-other
Champagne D E DE Smartt C T CT Ribeiro J M JM James A A AA
Proceedings of the National Academy of Sciences of the United States of America 19950101 3
The saliva of hematophagous insects contains a variety of pharmacologically active substances that counteract the normal hemostatic response to injury in vertebrate hosts. The yellow-fever mosquito, Aedes aegypti, secretes an apyrase that inhibits ADP-dependent platelet aggregation. Apyrase was purified as an active enzyme from adult female salivary glands and subjected to tryptic digestion, and the resulting peptides were sequenced. The amino acid sequences obtained match the conceptual transla ...[more]