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Demonstrating frequency-dependent transmission of sarcoptic mange in red foxes.

ABSTRACT: Understanding the relationship between disease transmission and host density is essential for predicting disease spread and control. Using long-term data on sarcoptic mange in a red fox Vulpes vulpes population, we tested long-held assumptions of density- and frequency-dependent direct disease transmission. We also assessed the role of indirect transmission. Contrary to assumptions typical of epidemiological models, mange dynamics are better explained by frequency-dependent disease transmission than by density-dependent transmission in this canid. We found no support for indirect transmission. We present the first estimates of R0 and age-specific transmission coefficients for mange in foxes. These parameters are important for managing this poorly understood but highly contagious and economically damaging disease.

SUBMITTER: Devenish-Nelson ES

PROVIDER: S-EPMC4272203 | biostudies-other | 2014 Oct

REPOSITORIES: biostudies-other

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Demonstrating frequency-dependent transmission of sarcoptic mange in red foxes.

Devenish-Nelson Eleanor S ES Richards Shane A SA Harris Stephen S Soulsbury Carl C Stephens Philip A PA

Biology letters 20141001 10

Understanding the relationship between disease transmission and host density is essential for predicting disease spread and control. Using long-term data on sarcoptic mange in a red fox Vulpes vulpes population, we tested long-held assumptions of density- and frequency-dependent direct disease transmission. We also assessed the role of indirect transmission. Contrary to assumptions typical of epidemiological models, mange dynamics are better explained by frequency-dependent disease transmission ...[more]

PMID: 25296930

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