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Primitive neuroectodermal tumor (PNET) of the lung in an adult woman.


ABSTRACT: Primary primitive neuroectodermal tumors (PNETs) are extremely rare in the lung and especially in adult women. We describe a case of PNET of the lung with aggressive behavior in 31-year-old woman. Diagnosis was based on histopathological and immunohistochemical studies, and confirmed by molecular genetic analysis of chromosome rearrangements in the EWSR1 gene region. Clinical follow-up, post-mortem findings, and differential diagnosis are also discussed.

SUBMITTER: Gachechiladze M 

PROVIDER: S-EPMC4289161 | biostudies-other | 2014

REPOSITORIES: biostudies-other

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Primitive neuroectodermal tumor (PNET) of the lung in an adult woman.

Gachechiladze Mariam M   Skarda Josef J   Ibrahim Maha M   Tichý Tomáš T   Flodr Patrik P   Latálová Pavla P   Ehrmann Jiří J   Trojanec Radek R   Kolář Zdenek Z  

World journal of surgical oncology 20141205


Primary primitive neuroectodermal tumors (PNETs) are extremely rare in the lung and especially in adult women. We describe a case of PNET of the lung with aggressive behavior in 31-year-old woman. Diagnosis was based on histopathological and immunohistochemical studies, and confirmed by molecular genetic analysis of chromosome rearrangements in the EWSR1 gene region. Clinical follow-up, post-mortem findings, and differential diagnosis are also discussed. ...[more]

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