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Placental amniotic epithelial cells and their therapeutic potential in liver diseases.


ABSTRACT: As a unique source of stem cells, there is a growing interest in amniotic epithelial (AE) cells. Placenta is readily available; in fact, it is often discarded following delivery. As such, it is without the ethical concerns of embryonic stem cells. Further advantages to AE include that AE cells do not demonstrate tumorigenicity upon transplantation, and are gifted with immunomodulatory and anti-inflammatory properties. Thus, AE cells have exceptional features for use as cell-based therapies for liver disease.

SUBMITTER: Tahan AC 

PROVIDER: S-EPMC4291892 | biostudies-other | 2014

REPOSITORIES: biostudies-other

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Placental amniotic epithelial cells and their therapeutic potential in liver diseases.

Tahan Asli Ceren AC   Tahan Veysel V  

Frontiers in medicine 20141208


As a unique source of stem cells, there is a growing interest in amniotic epithelial (AE) cells. Placenta is readily available; in fact, it is often discarded following delivery. As such, it is without the ethical concerns of embryonic stem cells. Further advantages to AE include that AE cells do not demonstrate tumorigenicity upon transplantation, and are gifted with immunomodulatory and anti-inflammatory properties. Thus, AE cells have exceptional features for use as cell-based therapies for l  ...[more]

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