Resolution of acute inflammation in the lung.
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ABSTRACT:
SUBMITTER: Levy BD
PROVIDER: S-EPMC4295924 | biostudies-other | 2014
REPOSITORIES: biostudies-other
Publications
Resolution of acute inflammation in the lung.
Levy Bruce D BD Serhan Charles N CN
Annual review of physiology 20131202
Acute inflammation in the lung is essential to health. So too is its resolution. In response to invading microbes, noxious stimuli, or tissue injury, an acute inflammatory response is mounted to protect the host. To limit inflammation and prevent collateral injury of healthy, uninvolved tissue, the lung orchestrates the formation of specialized proresolving mediators, specifically lipoxins, resolvins, protectins, and maresins. These immunoresolvents are agonists for resolution that interact with ...[more]
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