Enzymatic intracrine regulation of white adipose tissue.
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ABSTRACT:
SUBMITTER: DiSilvestro D
PROVIDER: S-EPMC4304678 | biostudies-other | 2014 Jul
REPOSITORIES: biostudies-other
Publications
Enzymatic intracrine regulation of white adipose tissue.
DiSilvestro David D Petrosino Jennifer J Aldoori Ayat A Melgar-Bermudez Emiliano E Wells Alexandra A Ziouzenkova Ouliana O
Hormone molecular biology and clinical investigation 20140701 1
Abdominal fat formation has become a permanent risk factor for metabolic syndrome and various cancers in one-third of the world's population of obese and even lean patients. Formation of abdominal fat involves additional mechanisms beyond an imbalance in energy intake and expenditure, which explains systemic obesity. In this review, we briefly summarized autonomous regulatory circuits that locally produce hormones from inactive precursors or nutrients for intra-/auto-/paracrine signaling in whit ...[more]
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