Ontology highlight
ABSTRACT:
SUBMITTER: Callahan R
PROVIDER: S-EPMC4307801 | biostudies-other | 2011 Feb
REPOSITORIES: biostudies-other
Callahan Rena R Hurvitz Sara S
Current opinion in obstetrics & gynecology 20110201 1
<h4>Purpose of review</h4>This review describes the current treatment of human epidermal growth factor receptor-2 (HER2)-positive breast cancer with a focus on recently reported clinical trials.Treatment of resistant disease and central nervous system metastases will be reviewed as will new agents that are being developed to target HER2-amplified breast cancers.<h4>Recent findings</h4>Recent studies evaluating trastuzumab-resistant breast cancer have shown a benefit of continuing trastuzumab wit ...[more]