Ontology highlight
ABSTRACT:
SUBMITTER: Cao R
PROVIDER: S-EPMC4308825 | biostudies-other | 2015 Feb
REPOSITORIES: biostudies-other
Cao Ruixue R Long Fei F Wang Liping L Xu Yuejuan Y Guo Ying Y Li Fen F Chen Sun S Sun Kun K Xu Rang R
DNA and cell biology 20141125 2
Heterotaxy syndrome, which causes significant morbidity and mortality, is a class of congenital disorders, in which normal left-right asymmetry cannot be properly established. To explore the role of copy number variants (CNVs) in the occurrence of heterotaxy syndrome, we recruited 93 heterotaxy patients and studied 12 of them by the Affymetrix Genome-Wide Human SNP 6.0 Array. The results were confirmed in the remaining 81 patients and 500 healthy children by quantitative real-time polymerase cha ...[more]