Ontology highlight
ABSTRACT:
SUBMITTER: Quan Y
PROVIDER: S-EPMC4313083 | biostudies-other | 2015 Feb
REPOSITORIES: biostudies-other
Quan Yizhou Y Xia Li L Shao Jiaxiang J Yin Shankai S Cheng C Yan CY Xia Weiliang W Gao Wei-Qiang WQ
Scientific reports 20150202
Hearing loss resulting from hair cell degeneration is a common disease that affects millions of people worldwide. Strategies to overcome the apparent irreversible hair cell loss in mammals become paramount for hearing protection. Here we reported that, by using a well-established gentamicin-induced hair cell loss model in vitro, adjudin, a multi-functional small molecule drug, protected cochlear hair cells from gentamicin damage. Immunohistochemistry, Western blotting and quantitative RT-PCR ana ...[more]