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Infectious causes of necrotizing enterocolitis.


ABSTRACT: Necrotizing enterocolitis (NEC) is the most common gastrointestinal emergency among premature infants. Although a large body of research has focused on understanding its pathogenesis, the exact mechanism has not been elucidated. Of particular interest is the potential causative role of infectious culprits in the development of NEC. A variety of reports describe bacterial, viral, and fungal infections occurring in association with NEC; however, no single organism has emerged as being definitively involved in NEC pathogenesis. In this review, the authors summarize the literature on infectious causes of NEC.

SUBMITTER: Coggins SA 

PROVIDER: S-EPMC4328138 | biostudies-other | 2015 Mar

REPOSITORIES: biostudies-other

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Infectious causes of necrotizing enterocolitis.

Coggins Sarah A SA   Wynn James L JL   Weitkamp Jörn-Hendrik JH  

Clinics in perinatology 20141127 1


Necrotizing enterocolitis (NEC) is the most common gastrointestinal emergency among premature infants. Although a large body of research has focused on understanding its pathogenesis, the exact mechanism has not been elucidated. Of particular interest is the potential causative role of infectious culprits in the development of NEC. A variety of reports describe bacterial, viral, and fungal infections occurring in association with NEC; however, no single organism has emerged as being definitively  ...[more]

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